The Yeast Formin Bnr1p Has Two Localization Regions That Show Spatially and Temporally Distinct Association with Septin Structures

摘要

Formins are conserved eukaryotic proteins that direct the nucleation and elongation of unbranched actin filaments. We define two nonoverlapping regions, Bnr1p-L1 (1-466) and Bnr1p-L2 (466-733) that can each localize to the bud neck independently of endogenous Bnr1p.